Vaneular®

Aging, Chronic Conditions, and Nerve Damage

When you're young and not dealing with chronic conditions, everything feels easy. Walking and running come naturally and dropping things rarely happens. Your senses are sharp, letting you react quickly to touch and sensations.

On the other hand, if you're aging or dealing with chronic conditions, you may experience changes that make daily activities more challenging. You might notice a weakening grip in your hands, along with numbness or tingling.¹ These changes often stem from age and sickness-related nerve issues, including neuropathy.²

Here’s how each health condition can lead to neuropathy:

• Aging 
  As you get older, your nerves ability to repair themselves slows down, and the protective coating around your nerves, known as myelin, starts to break down.^3,4
   
• Diabetes 
  Nearly 50% of diabetic patients will face neuropathy at some point. High blood sugar over time can trigger the buildup of harmful byproducts, leading to nerve damage and impaired nerve signaling.⁵
   
• High Cholesterol 
  Elevated levels of fats (lipids) in the blood can harm the nervous system by causing oxidative stress, inflammation, and poor blood circulation.⁶

What You Can Do to Help Your Nerves

Luckily, there are ways to help protect and nurture your nerves to reverse or slow down nerve damage before it becomes permanent.

Here are some tips to consider:

• Regular Check-Ups: Keep your health issues in check with routine visits to your healthcare provider.⁷
• Balanced Diet: Fuel your body with an array of foods rich in essential nutrients, like B vitamins, omega-3 fatty acids, and antioxidants. Incorporate leafy greens, nuts, and fatty fish into your meals.⁸
• Consistent Exercise: Get moving! A review of 41 studies found that exercise benefits people with neuropathy, especially those with diabetic peripheral neuropathy (DPN). ⁹ Exercise aided in improving balance, nerve function, and quality of life.⁹
• Quitting Smoking Quit smoking! Studies show that the longer someone smokes, the higher their chances of developing nerve pain, particularly for those with diabetes.¹⁰
• Limiting Alcohol Consumption: Alcohol can disrupt the absorption of essential nutrients like thiamine (vitamin B1) in your body.¹¹ Cutting back on alcohol may help prevent nerve damage and aid in the absorption of these vitamins.

Vitamin B-Complex (Vaneular^®) B vitamin supplementation, together with a healthy lifestyle, can help enhance nerve health by filling nutritional gaps and providing easily absorbed forms of B vitamins.

Consider Vitamin B-Complex (Vaneular^®)!

Vitamin B-Complex (Vaneular^®) is used to help treat deficiencies of vitamins B1, B2, B6, B12, and Nicotinic Acid manifested as: muscle pain, loss of reflexes in the hands, knees, ankles, calves and feet, and abnormal touch sensation such as burning and pricking.

References:

• ¹Feldman, E. L., Callaghan, B. C., Pop-Busui, R., Zochodne, D. W., Wright, D. E., Bennett, D. L., Bril, V., Russell, J. W., & Viswanathan, V. (2019). Diabetic neuropathy. Nature reviews. Disease primers, 5(1), 41. https://pubmed.ncbi.nlm.nih.gov/31197153/
• ²Brisset, M., & Nicolas, G. (2018). Peripheral neuropathies and aging. Neuropathies périphériques et vieillissement. Geriatrie et psychologie neuropsychiatrie du vieillissement, 16(4), 409–413. Accessed through: https://pubmed.ncbi.nlm.nih.gov/30563801/
• ³Peters, A. (2007c). The effects of normal aging on nerve fibers and neuroglia in the central nervous system. Brain Aging - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK3873/
• ⁴Braffett, B. H., Gubitosi-Klug, R. A., Albers, J. W., Feldman, E. L., Martin, C. L., White, N. H., Orchard, T. J., Lopes-Virella, M., Lachin, J. M., Pop-Busui, R., & DCCT/EDIC Research Group (2020). Risk Factors for Diabetic Peripheral Neuropathy and Cardiovascular Autonomic Neuropathy in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study. Diabetes, 69(5), 1000–1010. https://pubmed.ncbi.nlm.nih.gov/32051148/
• ⁵Yachmaneni, A., Jr, Jajoo, S., Mahakalkar, C., Kshirsagar, S., & Dhole, S. (2023). A Comprehensive Review of the Vascular Consequences of Diabetes in the Lower Extremities: Current Approaches to Management and Evaluation of Clinical Outcomes. Cureus, 15(10), e47525. Read more about this article
• ⁶Wu, S., Cao, X., He, R., & Xiong, K. (2012). Detrimental impact of hyperlipidemia on the peripheral nervous system: A novel target of medical epidemiological and fundamental research study. Neural regeneration research, 7(5), 392–399. https://pmc.ncbi.nlm.nih.gov/articles/PMC4350124/
• ⁷Neurological exam. (2019, November 19). Johns Hopkins Medicine.
  https://www.hopkinsmedicine.org/health/conditions-and-diseases/neurological-exam
• ⁸El Soury, M., Fornasari, B. E., Carta, G., Zen, F., Haastert-Talini, K., & Ronchi, G. (2021). The Role of Dietary Nutrients in Peripheral Nerve Regeneration. International journal of molecular sciences, 22(14), 7417. https://doi.org/10.3390/ijms22147417
• ⁹Streckmann, F., Balke, M., Cavaletti, G., Toscanelli, A., Bloch, W., Décard, B. F., Lehmann, H. C., & Faude, O. (2022). Exercise and Neuropathy: Systematic Review with Meta-Analysis. Sports medicine (Auckland, N.Z.), 52(5), 1043–1065. https://pubmed.ncbi.nlm.nih.gov/34964950/
• ¹⁰Çelik, S. B., Can, H., Sözmen, M. K., ?engezer, T., Kaplan, Y. C., Utlu, G., ?ener, A., Aybek Y?lmaz, A., & Aygün, O. (2017). Evaluation of the neuropathic pain in the smokers. Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology, 29(3), 122–126. https://pubmed.ncbi.nlm.nih.gov/29039152/
• ¹¹Martin, P. R., Singleton, C. K., & Hiller-Sturmhöfel, S. (2003). The role of thiamine deficiency in alcoholic brain disease. Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 27(2), 134–142.
• ¹²Vaneular® Product Information Leaflet. Date of Revision: Oct 2021.

B-Complex (Vaneular®) has Superior 5 B Vitamin Formulation!

1. Here’s what's inside each B-Complex (Vaneular^®) tablet:
   • Involved in the production and release of acetylcholine, a neurotransmitter required in conveying signals between nerve cells.¹²
   • Assists in the conversion of carbohydrate to energy.¹⁴
2. Riboflavin (Vitamin B2)
   • Essential for the formation of flavoproteins involved in energy release from carbohydrate, fat, and protein.¹²
   • Riboflavin deficiency is manifested as cheilosis (appearance of cracks or fissures at the corners of the mouth), glossitis (inflammation of the tongue) and dry, scaly skin.¹²
3. Pyridoxine (Vitamin B6)
   • Required in the formation of neurotransmitters such as serotonin, gamma amino butyric acid (GABA), dopamine, and epinephrine to facilitate normal nervous system function.¹²
   • Assists in the breakdown and utilization of energy from amino acids and protein.¹²
   • Deficiency of Vitamin B, is manifested as nausea, impaired immune function, skin disorders, mouth sores, weakness, mental depression, anemia, and epileptic convulsions.¹²
4. Cyanocobalamin (Vitamin B12)
   • Required for the synthesis of myelin, the white sheath that surrounds nerve fibers.¹²
   • Essential in the breakdown and utilization of energy from fatty acids.¹²
   • Deficiency of Vitamin B, is manifested as neuromuscular symptoms such as unsteadiness of the feet, poor muscle coordination and agitation.¹⁵
5. Nicotinic Acid (Vitamin B3)
   • An important requirement for DNA repair and calcium metabolism.¹²
   • Essential for energy release from carbohydrate, fat and protein.¹²
   • Deficiency may result in pellagra, a condition characterized by poor appetite, pigmented rash, a bright red tongue and neurological symptoms such as depression, headache, fatigue, and loss of memory.¹²